Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study

Observational studies have shown an association between obesity and venous thromboembolism (VTE) but it is not known if observed associations are causal, due to reverse causation or confounding bias. We conducted a Mendelian Randomization study of body mass index (BMI) and VTE. We identified 95 sing...

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Vydáno v:Hum Genet
Hlavní autoři: Lindström, Sara, Germain, Marine, Crous-Bou, Marta, Smith, Erin N., Morange, Pierre-Emmanuel, van Hylckama Vlieg, Astrid, de Haan, Hugoline G., Chasman, Daniel, Ridker, Paul, Brody, Jennifer, de Andrade, Mariza, Heit, John A, Tang, Weihong, DeVivo, Immaculata, Grodstein, Francine, Smith, Nicholas L., Tregouet, David, Kabrhel, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531049/
https://ncbi.nlm.nih.gov/pubmed/28528403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-017-1811-x
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