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Assessing the model transferability for prediction of transcription factor binding sites based on chromatin accessibility

BACKGROUND: Computational prediction of transcription factor (TF) binding sites in different cell types is challenging. Recent technology development allows us to determine the genome-wide chromatin accessibility in various cellular and developmental contexts. The chromatin accessibility profiles pr...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Liu, Sheng, Zibetti, Cristina, Wan, Jun, Wang, Guohua, Blackshaw, Seth, Qian, Jiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530957/
https://ncbi.nlm.nih.gov/pubmed/28750606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1769-7
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