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Regulated high efficiency expression of human interferon-alpha in Saccharomyces cerevisiae.

The 5' control region of the yeast phosphoglycerate kinase gene (PGK) was fused to the coding sequence of a human interferon-alpha. This PGK-interferon fusion was then introduced into yeast on a high copy number 2mu-based plasmid vector. Strains containing this plasmid produced a PGK-interferon-alph...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Tuite, M F, Dobson, M J, Roberts, N A, King, R M, Burke, D C, Kingsman, S M, Kingsman, A J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6329694/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1982.tb01215.x
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