Regulated high efficiency expression of human interferon-alpha in Saccharomyces cerevisiae.

The 5' control region of the yeast phosphoglycerate kinase gene (PGK) was fused to the coding sequence of a human interferon-alpha. This PGK-interferon fusion was then introduced into yeast on a high copy number 2mu-based plasmid vector. Strains containing this plasmid produced a PGK-interferon...

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Bibliographic Details
Main Authors: Tuite, M F, Dobson, M J, Roberts, N A, King, R M, Burke, D C, Kingsman, S M, Kingsman, A J
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC553094/
https://ncbi.nlm.nih.gov/pubmed/6329694
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