Tumor Necrosis Factor-α and IL-17A Activation Induces Pericyte-Mediated Basement Membrane Remodeling in Human Neutrophilic Dermatoses

Sweet syndrome (SS) is a prototypical neutrophilic dermatosis, a class of inflammatory diseases marked by elevated levels of tumor necrosis factor (TNF)-α and IL-17A, pathologic neutrophil recruitment, and microvascular remodeling. Histologic analyses of four matrix proteins—collagen I and IV, lamin...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Lauridsen, Holly M., Pellowe, Amanda S., Ramanathan, Anand, Liu, Rebecca, Miller-Jensen, Kathryn, McNiff, Jennifer M., Pober, Jordan S., Gonzalez, Anjelica L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530916/
https://ncbi.nlm.nih.gov/pubmed/28609645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.04.008
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