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Endothelial cell-secreted MIF reduces pericyte contractility and enhances neutrophil extravasation

Dysregulated neutrophil extravasation contributes to the pathogenesis of many inflammatory disorders. Pericytes (PCs) have been implicated in the regulation of neutrophil transmigration, and previous work demonstrates that endothelial cell (EC)-derived signals reduce PC barrier function; however, th...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Pellowe, Amanda S., Sauler, Maor, Hou, Yue, Merola, Jonathan, Liu, Rebecca, Calderon, Brenda, Lauridsen, Holly M., Harris, Mariah R., Leng, Lin, Zhang, Yi, Tilstam, Pathricia V., Pober, Jordan S., Bucala, Richard, Lee, Patty J., Gonzalez, Anjelica L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338650/
https://ncbi.nlm.nih.gov/pubmed/30252532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800480R
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