Endothelium-Independent Primitive Myxoid Vascularization Creates Invertebrate-Like Channels to Maintain Blood Supply in Optic Gliomas

Optic gliomas are brain tumors characterized by slow growth, progressive loss of vision, and limited therapeutic options. Optic gliomas contain various amounts of myxoid matrix, which can represent most of the tumor mass. We sought to investigate biological function and protein structure of the myxo...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Snuderl, Matija, Zhang, Guoan, Wu, Pamela, Jennings, Tara S., Shroff, Seema, Ortenzi, Valerio, Jain, Rajan, Cohen, Benjamin, Reidy, Jason J., Dushay, Mitchell S., Wisoff, Jeffrey H., Harter, David H., Karajannis, Matthias A., Fenyo, David, Neubert, Thomas A., Zagzag, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530906/
https://ncbi.nlm.nih.gov/pubmed/28606795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.04.004
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