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Screening for EphB signaling effectors using SILAC with a linear ion trap-Orbitrap mass spectrometer

Eph receptors play important roles in development, neural plasticity and cancer. We used an Orbitrap mass spectrometer and Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) to identify and quantify 204 proteins with significantly changed abundance in anti-phosphotyrosine immunoprecipita...

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Detalhes bibliográficos
Main Authors: Zhang, Guoan, Fenyö, David, Neubert, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673988/
https://ncbi.nlm.nih.gov/pubmed/18816084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr800255a
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