Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes.

The circulating T lymphocytes of a female child with recurrent opportunistic infections were normal in number and phenotype but exhibited poor proliferation and decreased synthesis of the T-cell growth factor interleukin (IL) 2 in response to mitogens. Recombinant IL-2 fully restored the proliferati...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chatila, T, Castigli, E, Pahwa, R, Pahwa, S, Chirmule, N, Oyaizu, N, Good, R A, Geha, R S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55309/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2263604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.10033
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