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Single-Quantum-Dot Tracking Reveals Altered Membrane Dynamics of an Attention-Deficit/Hyperactivity-Disorder-Derived Dopamine Transporter Coding Variant

The presynaptic, cocaine- and amphetamine-sensitive dopamine (DA) transporter (DAT, SLC6A3) controls the intensity and duration of synaptic dopamine signals by rapid clearance of DA back into presynaptic nerve terminals. Abnormalities in DAT-mediated DA clearance have been linked to a variety of neu...

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Bibliographische Detailangaben
Veröffentlicht in:ACS Chem Neurosci
Hauptverfasser: Kovtun, Oleg, Sakrikar, Dhananjay, Tomlinson, Ian D., Chang, Jerry C., Arzeta-Ferrer, Xochitl, Blakely, Randy D., Rosenthal, Sandra J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530757/
https://ncbi.nlm.nih.gov/pubmed/25747272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500202c
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