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Mass spectrometry captures structural intermediates in protein fiber self-assembly

Self-assembling proteins, the basis for a broad range of biological scaffolds, are challenging to study using most structural biology approaches. Here we show that mass spectrometry (MS) in combination with MD simulations captures structural features of short-lived oligomeric intermediates in spider...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Landreh, Michael, Andersson, Marlene, Marklund, Erik G., Jia, Qiupin, Meng, Qing, Johansson, Jan, Robinson, Carol V., Rising, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530726/
https://ncbi.nlm.nih.gov/pubmed/28184384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc00307b
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