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Mass spectrometry captures structural intermediates in protein fiber self-assembly

Self-assembling proteins, the basis for a broad range of biological scaffolds, are challenging to study using most structural biology approaches. Here we show that mass spectrometry (MS) in combination with MD simulations captures structural features of short-lived oligomeric intermediates in spider...

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Publicat a:Chem Commun (Camb)
Autors principals: Landreh, Michael, Andersson, Marlene, Marklund, Erik G., Jia, Qiupin, Meng, Qing, Johansson, Jan, Robinson, Carol V., Rising, Anna
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530726/
https://ncbi.nlm.nih.gov/pubmed/28184384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc00307b
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