Active viral genes in transformed cells lie close to the nuclear cage.

Nuclear DNA is looped by attachment to a matrix or cage. Using nine different lines transformed by polyoma or avian sarcoma virus, we have mapped viral sequences integrated within these loops. In all lines that contain high concentrations of viral transcripts and express the transformed phenotype, t...

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Detalhes bibliográficos
Main Authors: Cook, P R, Lang, J, Hayday, A, Lania, L, Fried, M, Chiswell, D J, Wyke, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC553066/
https://ncbi.nlm.nih.gov/pubmed/6329681
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