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Loss of functional large T-antigen and free viral genomes from cells transformed in vitro by polyoma virus after passage in vivo as tumor cells.

We have analyzed the state, arrangement, and expression of polyoma viral DNA sequences in a number of in vitro-transformed Fischer rat cells before and after growth in vivo as tumour cells. When the in vitro lines used to induce the tumors contained only a single insert of viral sequences and did no...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Lania, L, Hayday, A, Fried, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171351/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6268833/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.39.2.422-431.1981
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