MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress

The partner and localiser of BRCA2 (PALB2) plays important roles in the maintenance of genome integrity and protection against cancer. Although PALB2 is commonly described as a repair factor recruited to sites of DNA breaks, recent studies provide evidence that PALB2 also associates with unperturbed...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Bleuyard, Jean-Yves, Fournier, Marjorie, Nakato, Ryuichiro, Couturier, Anthony M., Katou, Yuki, Ralf, Christine, Hester, Svenja S., Dominguez, Daniel, Rhodes, Daniela, Humphrey, Timothy C., Shirahige, Katsuhiko, Esashi, Fumiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2017
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530651/
https://ncbi.nlm.nih.gov/pubmed/28673974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620208114
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