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ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair
The partner and localizer of breast cancer 2 susceptibility protein (PALB2) is crucial for the repair of DNA damage by homologous recombination. Here, we report that chromatin-association motif (ChAM), an evolutionarily conserved motif in PALB2, is necessary and sufficient to mediate its chromatin a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271335/ https://ncbi.nlm.nih.gov/pubmed/22193777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.243 |
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