MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress

The partner and localiser of BRCA2 (PALB2) plays important roles in the maintenance of genome integrity and protection against cancer. Although PALB2 is commonly described as a repair factor recruited to sites of DNA breaks, recent studies provide evidence that PALB2 also associates with unperturbed...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Bleuyard, Jean-Yves, Fournier, Marjorie, Nakato, Ryuichiro, Couturier, Anthony M., Katou, Yuki, Ralf, Christine, Hester, Svenja S., Dominguez, Daniel, Rhodes, Daniela, Humphrey, Timothy C., Shirahige, Katsuhiko, Esashi, Fumiko
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530651/
https://ncbi.nlm.nih.gov/pubmed/28673974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620208114
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki