MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress

The partner and localiser of BRCA2 (PALB2) plays important roles in the maintenance of genome integrity and protection against cancer. Although PALB2 is commonly described as a repair factor recruited to sites of DNA breaks, recent studies provide evidence that PALB2 also associates with unperturbed...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Bleuyard, Jean-Yves, Fournier, Marjorie, Nakato, Ryuichiro, Couturier, Anthony M., Katou, Yuki, Ralf, Christine, Hester, Svenja S., Dominguez, Daniel, Rhodes, Daniela, Humphrey, Timothy C., Shirahige, Katsuhiko, Esashi, Fumiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2017
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530651/
https://ncbi.nlm.nih.gov/pubmed/28673974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620208114
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