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Synthesis of the heterocyclic core of the D-series GE2270

A straightforward enantiomerically pure synthesis of the heterocyclic core of the D-series GE2270 is reported. The synthetic strategy combines the Hantzsch thiazole’s building condensation with a cross-coupling reaction including direct C–H hetarylation to build and connect step-by-step thiazolyl mo...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Berini, Christophe, Martin, Thibaut, Lassalas, Pierrik, Marsais, Francis, Baudequin, Christine, Hoarau, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530635/
https://ncbi.nlm.nih.gov/pubmed/28781706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.137
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