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Synthesis of oligonucleotides on a soluble support

Oligonucleotides are usually prepared in lab scale on a solid support with the aid of a fully automated synthesizer. Scaling up of the equipment has allowed industrial synthesis up to kilogram scale. In spite of this, solution-phase synthesis has received continuous interest, on one hand as a techni...

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Библиографические подробности
Опубликовано в: :Beilstein J Org Chem
Главный автор: Lönnberg, Harri
Формат: Artigo
Язык:Inglês
Опубликовано: Beilstein-Institut 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530625/
https://ncbi.nlm.nih.gov/pubmed/28781703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.134
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