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Preparation of a disulfide-linked precipitative soluble support for solution-phase synthesis of trimeric oligodeoxyribonucleotide 3´-(2-chlorophenylphosphate) building blocks

The preparation of a disulfide-tethered precipitative soluble support and its use for solution-phase synthesis of trimeric oligodeoxyribonucleotide 3´-(2-chlorophenylphosphate) building blocks is described. To obtain the building blocks, N-acyl protected 2´-deoxy-5´-O-(4,4´-dimethoxytrityl)ribonucle...

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Bibliografische gegevens
Gepubliceerd in:Beilstein J Org Chem
Hoofdauteurs: Jabgunde, Amit M, Molina, Alejandro Gimenez, Virta, Pasi, Lönnberg, Harri
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Beilstein-Institut 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660909/
https://ncbi.nlm.nih.gov/pubmed/26664575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.171
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