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A speedy route to sterically encumbered, benzene-fused derivatives of privileged, naturally occurring hexahydropyrrolo[1,2-b]isoquinoline

A series of 15 benzene-fused hexahydropyrrolo[1,2-b]isoquinolonic acids with substantial degree of steric encumbrance has been prepared via a novel variant of the Castagnoli–Cushman reaction of homophthalic anhydride (HPA) and various indolenines. The employment of a special kind of a cyclic imine c...

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Foilsithe in:Beilstein J Org Chem
Main Authors: Bakulina, Olga, Ivanov, Alexander, Suslonov, Vitalii, Dar’in, Dmitry, Krasavin, Mikhail
Formáid: Artigo
Teanga:Inglês
Foilsithe: Beilstein-Institut 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530605/
https://ncbi.nlm.nih.gov/pubmed/28781707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.138
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