Altered expression of cellular proliferation, apoptosis and the cell cycle-related genes in lung cancer cells with acquired resistance to EGFR tyrosine kinase inhibitors

Non-small cell lung cancers harboring somatic gain-of-function mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase domain respond well to treatment with EGFR tyrosine kinase inhibitors (TKIs) including gefitinib and erlotinib. However, all patients who experience a marked improv...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Lee, Tae-Gul, Jeong, Eun-Hui, Min, Il Jae, Kim, Seo Yun, Kim, Hye-Ryoun, Kim, Cheol Hyeon
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530116/
https://ncbi.nlm.nih.gov/pubmed/28781659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6428
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