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Altered expression of cellular proliferation, apoptosis and the cell cycle-related genes in lung cancer cells with acquired resistance to EGFR tyrosine kinase inhibitors

Non-small cell lung cancers harboring somatic gain-of-function mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase domain respond well to treatment with EGFR tyrosine kinase inhibitors (TKIs) including gefitinib and erlotinib. However, all patients who experience a marked improv...

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Bibliografske podrobnosti
izdano v:Oncol Lett
Main Authors: Lee, Tae-Gul, Jeong, Eun-Hui, Min, Il Jae, Kim, Seo Yun, Kim, Hye-Ryoun, Kim, Cheol Hyeon
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530116/
https://ncbi.nlm.nih.gov/pubmed/28781659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6428
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