Characterization of the aminopyridine derivative KRC-180 as a JAK2 inhibitor

Janus kinase 2 (JAK2) is a non-receptor tyrosine kinase that regulates the signal transducer and activator of transcription (STAT) signaling pathway. Deregulation of JAK2 signaling has previously been observed in hematologic malignancies, including erythroleukemia. In the present study, an aminopyri...

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Udgivet i:Oncol Lett
Main Authors: Yoon, Kyoung Bin, Cho, Sung Yun, An, Su Jin, Park, Kyeong Ryang, Lee, Hyo Jeong, Yoon, Hae Sung, Lee, Sun-Mi, Kim, Yong-Chul, Han, Sun-Young
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529941/
https://ncbi.nlm.nih.gov/pubmed/28789350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6353
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