Targeting MRP4 expression by anti-androgen treatment reverses MRP4-mediated docetaxel resistance in castration-resistant prostate cancer

It has been demonstrated that docetaxel (DTX) may improve the overall survival of patients with castration-resistant prostate cancer (CRPC). However, its effectiveness is limited with time, and tumor escape is eventually inevitable. DTX resistance is the main reason for the failure of chemotherapy f...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Li, Yun-Fei, Ji, Hui-Hua, Zhang, Zheng-Long, Zhang, Tao-Tao, Gan, Wei, Zhang, Shao-Feng
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529894/
https://ncbi.nlm.nih.gov/pubmed/28789405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6357
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