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Segmental trisomy of chromosome 17: A mouse model of human aneuploidy syndromes
Triplication of whole autosomes or large autosomal segments is detrimental to the development of a mammalian embryo. The trisomy of human chromosome (Chr) 21, known as Down's syndrome, is regularly associated with mental retardation and a variable set of other developmental anomalies. Several m...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC552979/ https://ncbi.nlm.nih.gov/pubmed/15755806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500802102 |
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