A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs

Unfertilized vertebrate eggs are arrested in metaphase of meiosis II with high cyclin B/Cdc2 activity to prevent parthenogenesis. Until fertilization, exit from metaphase is blocked by an activity called cytostatic factor (CSF), which stabilizes cyclin B by inhibiting the anaphase-promoting complex...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Tung, Jeffrey J., Hansen, David V., Ban, Kenneth H., Loktev, Alexander V., Summers, Matthew K., Adler, John R., Jackson, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552977/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15753281/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0501108102
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