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How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor

<p>Abstract</p> <p>Oocytes from higher chordates, including man and nearly all mammals, arrest at metaphase of the second meiotic division before fertilization. This arrest is due to an activity that has been termed 'Cytostatic Factor'. Cytostatic Factor maintains arrest through preventing loss in M...

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Bibliografiske detaljer
Principais autores: Jones Keith T, Madgwick Suzanne
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2007-01-01
Serier:Cell Division
Online adgang:http://www.celldiv.com/content/2/1/4
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