The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion

Long noncoding RNAs play a pivotal role in T-helper cell development but little is known about their roles in Treg differentiation and functions during the progression of hepatocellular carcinoma (HCC). Here, we show that lnc-epidermal growth factor receptor (EGFR) upregulation in Tregs correlates p...

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Publicat a:Nat Commun
Autors principals: Jiang, Runqiu, Tang, Junwei, Chen, Yun, Deng, Lei, Ji, Jie, Xie, Yu, Wang, Ke, Jia, Wei, Chu, Wen-Ming, Sun, Beicheng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529670/
https://ncbi.nlm.nih.gov/pubmed/28541302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15129
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