Comprehensive analysis of long noncoding RNA (lncRNA)-chromatin interactions reveals lncRNA functions dependent on binding diverse regulatory elements

Over the past decade, thousands of long noncoding RNAs (lncRNAs) have been identified, many of which play crucial roles in normal physiology and human disease. LncRNAs can interact with chromatin and then recruit protein complexes to remodel chromatin states, thus regulating gene expression. However...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Guanxiong, Lan, Yujia, Xie, Aimin, Shi, Jian, Zhao, Hongying, Xu, Liwen, Zhu, Shiwei, Luo, Tao, Zhao, Tingting, Xiao, Yun, Li, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Computational Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816106/
https://ncbi.nlm.nih.gov/pubmed/31484726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008732
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