Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression

We compared gene expression in low and high-grade intraepithelial dysplastic polyps from pigs carrying an APC (1311) truncating mutation orthologous to human APC (1309), analysing whole samples and microdissected dysplastic epithelium. Gene set enrichment analysis revealed differential expression of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Flisikowska, Tatiana, Stachowiak, Monika, Xu, Hongen, Wagner, Alexandra, Hernandez-Caceres, Alejandra, Wurmser, Christine, Perleberg, Carolin, Pausch, Hubert, Perkowska, Anna, Fischer, Konrad, Frishman, Dmitrij, Fries, Ruedi, Switonski, Marek, Kind, Alexander, Saur, Dieter, Schnieke, Angelika, Flisikowski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529429/
https://ncbi.nlm.nih.gov/pubmed/28747659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06741-8
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