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Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle

BACKGROUND: Cattle breeding populations are susceptible to the propagation of recessive diseases. Individual sires generate tens of thousands of progeny via artificial insemination. The frequency of deleterious alleles carried by such sires may increase considerably within few generations. Deleterio...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Pausch, Hubert, Schwarzenbacher, Hermann, Burgstaller, Johann, Flisikowski, Krzysztof, Wurmser, Christine, Jansen, Sandra, Jung, Simone, Schnieke, Angelika, Wittek, Thomas, Fries, Ruedi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403906/
https://ncbi.nlm.nih.gov/pubmed/25927203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1483-7
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