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Effect of the nanoformulation of siRNA-lipid assemblies on their cellular uptake and immune stimulation
Two lipid-based nanoformulations have been used to date in clinical studies: lipoplexes and lipid nanoparticles (LNPs). In this study, we prepared small interfering RNA (siRNA)-loaded carriers using lipid components of the same composition to form molecular assemblies of differing structures, and ev...
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| Publicado no: | Int J Nanomedicine |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5529365/ https://ncbi.nlm.nih.gov/pubmed/28790820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S136426 |
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