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Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma Germline mutations in Ewing sarcoma

PURPOSE: Ewing sarcoma is a highly malignant small round blue cell tumor that predominantly affects the adolescent and young adult population. It has long been suspected that a genetic predisposition exists for this cancer, but the germline genetic underpinnings of this disease have not been well es...

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Detalhes bibliográficos
Publicado no:Genet Med
Main Authors: Brohl, Andrew S, Patidar, Rajesh, Turner, Clesson E, Wen, Xinyu, Song, Young K, Wei, Jun S, Calzone, Kathleen A, Khan, Javed
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529247/
https://ncbi.nlm.nih.gov/pubmed/28125078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2016.206
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