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Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer

The precise mechanism by which binding of tumor necrosis factor ligands to the extracellular domain of their corresponding receptors transmits signals across the plasma membrane has remained elusive. Recent studies have proposed that activation of several tumor necrosis factor receptors, including D...

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Vydáno v:Biophys J
Hlavní autoři: Vunnam, Nagamani, Campbell-Bezat, Cecily Kristine, Lewis, Andrew K., Sachs, Jonathan N.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529174/
https://ncbi.nlm.nih.gov/pubmed/28746849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.038
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