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Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer

The precise mechanism by which binding of tumor necrosis factor ligands to the extracellular domain of their corresponding receptors transmits signals across the plasma membrane has remained elusive. Recent studies have proposed that activation of several tumor necrosis factor receptors, including D...

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Publicat a:Biophys J
Autors principals: Vunnam, Nagamani, Campbell-Bezat, Cecily Kristine, Lewis, Andrew K., Sachs, Jonathan N.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529174/
https://ncbi.nlm.nih.gov/pubmed/28746849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.038
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