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Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer

The precise mechanism by which binding of tumor necrosis factor ligands to the extracellular domain of their corresponding receptors transmits signals across the plasma membrane has remained elusive. Recent studies have proposed that activation of several tumor necrosis factor receptors, including D...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Vunnam, Nagamani, Campbell-Bezat, Cecily Kristine, Lewis, Andrew K., Sachs, Jonathan N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529174/
https://ncbi.nlm.nih.gov/pubmed/28746849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.038
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