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A viral scaffolding protein triggers portal ring oligomerization and incorporation during procapsid assembly

Most double-stranded DNA viruses package genetic material into empty precursor capsids (or procapsids) through a dodecameric portal protein complex that occupies 1 of the 12 vertices of the icosahedral lattice. Inhibiting incorporation of the portal complex prevents the formation of infectious virio...

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Bibliografski detalji
Izdano u:Sci Adv
Glavni autori: Motwani, Tina, Lokareddy, Ravi K., Dunbar, Carmen A., Cortines, Juliana R., Jarrold, Martin F., Cingolani, Gino, Teschke, Carolyn M.
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529062/
https://ncbi.nlm.nih.gov/pubmed/28782023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700423
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