Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis

Testicular necrosis is a sensitive endpoint for cadmium (Cd(2+), Cd) toxicity across all species tested. Resistance to Cd-induced testicular damage is a recessive trait assigned to the Cdm locus on mouse chromosome 3. We first narrowed the Cdm-gene-containing region to 880 kb. SNP analysis of this r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dalton, Timothy P., He, Lei, Wang, Bin, Miller, Marian L., Jin, Li, Stringer, Keith F., Chang, Xiaoqing, Baxter, C. Stuart, Nebert, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552906/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15722412/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406085102
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