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Generation of a Slc39a8 Hypomorph Mouse: Markedly Decreased ZIP8 Zn(2+)/(HCO(3)(–))(2) Transporter Expression

Previously this laboratory has identified the mouse Slc39a8 gene encoding the ZIP8 transporter, important in cadmium uptake. ZIP8 functions endogenously as a electroneutral Zn(2+)/(HCO(3)(–))(2) symporter, moving both ions into the cell. The overall physiological importance of ZIP8 remains unclear....

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Detalhes bibliográficos
Main Authors: Wang, Bin, He, Lei, Dong, Hongbin, Dalton, Timothy P., Nebert, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136049/
https://ncbi.nlm.nih.gov/pubmed/21658371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.05.134
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