Cd(2+) versus Zn(2+) Uptake by the ZIP8 HCO(3)(−)-Dependent Symporter: Kinetics, Electrogenicity and Trafficking

The mouse Slc39a8 gene encodes the ZIP8 transporter, which has been shown to be a divalent cation/HCO(3)(−) symporter. Using ZIP8 cRNA-injected Xenopus oocyte cultures, we show herein that: [a] ZIP8-mediated cadmium (Cd(2+)) and zinc (Zn(2+)) uptake have Vmax values of 1.8 ± 0.08 and 1.0 ± 0.08 pmol...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Liu, Zhiwei, Li, Hong, Soleimani, Manoocher, Girijashanker, Kuppuswami, Reed, Jodie M., He, Lei, Dalton, Timothy P., Nebert, Daniel W.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212618/
https://ncbi.nlm.nih.gov/pubmed/18037372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.11.067
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