Antagonist of growth hormone-releasing hormone induces apoptosis in LNCaP human prostate cancer cells through a Ca(2+)-dependent pathway

Antagonists of growth hormone-releasing hormone (GHRH) exert antiproliferative effects directly on cancer cells, which are mediated by the tumoral GHRH receptors. However, the signal transduction pathways involved in antiproliferative effect of GHRH antagonists have not yet been elucidated. We used...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rekasi, Zoltan, Czompoly, Tamas, Schally, Andrew V., Boldizsar, Ferenc, Varga, Jozsef L., Zarandi, Marta, Berki, Timea, Horvath, Reka A., Nemeth, Peter
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552899/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15728367/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0410006102
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