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Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer
The Homologous Recombination (HR) pathway is crucial for the repair of DNA double‐strand breaks (DSBs) generated during DNA replication. Defects in HR repair have been linked to the initiation and development of a wide variety of human malignancies, and exploited in chemical, radiological and target...
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| Publicado no: | Mol Oncol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528935/ https://ncbi.nlm.nih.gov/pubmed/26456802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.09.007 |
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