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Transcriptional profiling of dividing tumor cells detects intratumor heterogeneity linked to cell proliferation in a brain tumor model

Intratumor heterogeneity is a primary feature of high‐grade gliomas, complicating their therapy. As accumulating evidence suggests that intratumor heterogeneity is a consequence of cellular subsets with different cycling frequencies, we developed a method for transcriptional profiling of gliomas, us...

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Vydáno v:Mol Oncol
Hlavní autoři: Endaya, Berwini B., Lam, Paula Y.P., Meedeniya, Adrian C.B., Neuzil, Jiri
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528932/
https://ncbi.nlm.nih.gov/pubmed/26388584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.09.001
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