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Dystrophin Glycoprotein Complex Sequesters Yap to Inhibit Cardiomyocyte Proliferation
The regenerative capacity of the adult mammalian heart is limited because of the reduced ability of cardiomyocytes (CMs) to progress through mitosis(1). The regenerative capacity of endogenous CMs exists at birth but is lost postnatally, with subsequent organ growth occurring through CM hypertrophy(...
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| Publicado no: | Nature |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528853/ https://ncbi.nlm.nih.gov/pubmed/28581498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22979 |
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