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Dystrophin Glycoprotein Complex Sequesters Yap to Inhibit Cardiomyocyte Proliferation

The regenerative capacity of the adult mammalian heart is limited because of the reduced ability of cardiomyocytes (CMs) to progress through mitosis(1). The regenerative capacity of endogenous CMs exists at birth but is lost postnatally, with subsequent organ growth occurring through CM hypertrophy(...

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Bibliographic Details
Published in:Nature
Main Authors: Morikawa, Yuka, Heallen, Todd, Leach, John, Xiao, Yang, Martin, James F.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528853/
https://ncbi.nlm.nih.gov/pubmed/28581498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22979
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