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T‐cell receptor gene therapy — ready to go viral?

T lymphocytes can be redirected to recognize a tumor target and harnessed to combat cancer by genetic introduction of T‐cell receptors of a defined specificity. This approach has recently mediated encouraging clinical responses in patients with cancers previously regarded as incurable. However, desp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Oncol
Hauptverfasser: Karpanen, Terhi, Olweus, Johanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528733/
https://ncbi.nlm.nih.gov/pubmed/26548533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.10.006
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