Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress

Both Myc and Ras oncogenes impact cellular metabolism, deregulate redox homeostasis and trigger DNA replication stress (RS) that compromises genomic integrity. However, how are such oncogene‐induced effects evoked and temporally related, to what extent are these kinetic parameters shared by Myc and...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Maya-Mendoza, Apolinar, Ostrakova, Jitka, Kosar, Martin, Hall, Arnaldur, Duskova, Pavlina, Mistrik, Martin, Merchut-Maya, Joanna Maria, Hodny, Zdenek, Bartkova, Jirina, Christensen, Claus, Bartek, Jiri
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2014
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528704/
https://ncbi.nlm.nih.gov/pubmed/25435281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.11.001
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