Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress

Both Myc and Ras oncogenes impact cellular metabolism, deregulate redox homeostasis and trigger DNA replication stress (RS) that compromises genomic integrity. However, how are such oncogene‐induced effects evoked and temporally related, to what extent are these kinetic parameters shared by Myc and...

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Bibliografische gegevens
Gepubliceerd in:Mol Oncol
Hoofdauteurs: Maya-Mendoza, Apolinar, Ostrakova, Jitka, Kosar, Martin, Hall, Arnaldur, Duskova, Pavlina, Mistrik, Martin, Merchut-Maya, Joanna Maria, Hodny, Zdenek, Bartkova, Jirina, Christensen, Claus, Bartek, Jiri
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2014
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528704/
https://ncbi.nlm.nih.gov/pubmed/25435281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.11.001
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