Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress

Both Myc and Ras oncogenes impact cellular metabolism, deregulate redox homeostasis and trigger DNA replication stress (RS) that compromises genomic integrity. However, how are such oncogene‐induced effects evoked and temporally related, to what extent are these kinetic parameters shared by Myc and...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Maya-Mendoza, Apolinar, Ostrakova, Jitka, Kosar, Martin, Hall, Arnaldur, Duskova, Pavlina, Mistrik, Martin, Merchut-Maya, Joanna Maria, Hodny, Zdenek, Bartkova, Jirina, Christensen, Claus, Bartek, Jiri
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528704/
https://ncbi.nlm.nih.gov/pubmed/25435281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.11.001
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