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Acid ceramidase is associated with an improved prognosis in both DCIS and invasive breast cancer

Acid ceramidase (ASAH1) a key enzyme of sphingolipid metabolism converting pro‐apoptotic ceramide to sphingosine has been shown to be overexpressed in various cancers. We previously demonstrated higher expression of ASAH1 in ER positive compared to ER negative breast cancer. In the current study we...

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Библиографические подробности
Опубликовано в: :Mol Oncol
Главные авторы: Sänger, Nicole, Ruckhäberle, Eugen, Györffy, Balazs, Engels, Knut, Heinrich, Tomas, Fehm, Tanja, Graf, Anna, Holtrich, Uwe, Becker, Sven, Karn, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528695/
https://ncbi.nlm.nih.gov/pubmed/25131496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.07.016
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