Acid ceramidase is associated with an improved prognosis in both DCIS and invasive breast cancer

Acid ceramidase (ASAH1) a key enzyme of sphingolipid metabolism converting pro‐apoptotic ceramide to sphingosine has been shown to be overexpressed in various cancers. We previously demonstrated higher expression of ASAH1 in ER positive compared to ER negative breast cancer. In the current study we...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Sänger, Nicole, Ruckhäberle, Eugen, Györffy, Balazs, Engels, Knut, Heinrich, Tomas, Fehm, Tanja, Graf, Anna, Holtrich, Uwe, Becker, Sven, Karn, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528695/
https://ncbi.nlm.nih.gov/pubmed/25131496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.07.016
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