Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling

Aldehyde dehydrogenase (ALDH) 1A enzymes produce retinoic acid (RA), a transcription induction molecule. To investigate if ALDH1A1 or ALDH1A3‐mediated RA signaling has an active role in breast cancer tumorigenesis, we performed gene expression and tumor xenograft studies. Analysis of breast patient...

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Publicat a:Mol Oncol
Autors principals: Marcato, Paola, Dean, Cheryl A., Liu, Rong-Zong, Coyle, Krysta M., Bydoun, Moamen, Wallace, Melissa, Clements, Derek, Turner, Colin, Mathenge, Edward G., Gujar, Shashi A., Giacomantonio, Carman A., Mackey, John R., Godbout, Roseline, Lee, Patrick W.K.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528683/
https://ncbi.nlm.nih.gov/pubmed/25106087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.07.010
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