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Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling

Aldehyde dehydrogenase (ALDH) 1A enzymes produce retinoic acid (RA), a transcription induction molecule. To investigate if ALDH1A1 or ALDH1A3‐mediated RA signaling has an active role in breast cancer tumorigenesis, we performed gene expression and tumor xenograft studies. Analysis of breast patient...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Marcato, Paola, Dean, Cheryl A., Liu, Rong-Zong, Coyle, Krysta M., Bydoun, Moamen, Wallace, Melissa, Clements, Derek, Turner, Colin, Mathenge, Edward G., Gujar, Shashi A., Giacomantonio, Carman A., Mackey, John R., Godbout, Roseline, Lee, Patrick W.K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528683/
https://ncbi.nlm.nih.gov/pubmed/25106087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.07.010
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